Drug Regulator Issues Fresh Advisory on Painkiller Abuse and Kidney Risks

NEW DELHI, September 28: India’s drug regulator has warned against the indiscriminate, repeated or prolonged use of painkillers and antibiotics, highlighting the risk of kidney complications and other adverse health effects.

The recently issued advisory says commonly used non-steroidal anti-inflammatory drugs (NSAIDs) and antibiotics should be taken only when medically necessary, in the correct dose and for an appropriate duration under the supervision of a qualified medical professional.

Painkiller Abuse Can Damage Kidneys

Repeated or prolonged use of painkillers without medical supervision can adversely affect kidney function.

NSAIDs are widely used to treat pain, inflammation and fever, but inappropriate consumption can reduce blood flow to the kidneys and increase the risk of kidney injury, particularly among vulnerable patients.

People should therefore avoid using such medicines repeatedly without consulting a doctor.

Lowest Effective Dose Recommended

Healthcare professionals have been advised to prescribe NSAIDs at the lowest effective dose for the shortest appropriate duration.

Doctors should consider a patient’s age, medical history, existing diseases, other medicines being taken and potential risk factors before prescribing these drugs.

Extra caution is recommended for people who may already be vulnerable to kidney problems.

People With Kidney Disease Need Extra Caution

Individuals with pre-existing kidney disease or other risk factors for renal impairment should inform their doctor before using NSAIDs.

Older adults, people with certain chronic illnesses and patients taking multiple medicines may require additional monitoring.

The advisory stresses that medicines commonly available for pain relief should not automatically be considered harmless.

Antibiotic Self-Medication Also Discouraged

The regulator has also warned against taking antibiotics without medical advice.

Antibiotics should only be used when there is a clinical reason to prescribe them and should be taken in the recommended dose for the prescribed duration.

Using antibiotics unnecessarily, particularly for illnesses where they do not provide a benefit, can expose patients to avoidable side effects.

Viral Infections Often Do Not Require Antibiotics

People have been advised against taking antibiotics automatically for common viral illnesses.

Conditions such as many uncomplicated viral infections do not respond to antibiotics because these medicines are designed to treat bacterial infections.

Taking antibiotics when they are not required can contribute to unnecessary adverse effects and wider public-health concerns.

Pharmacies Asked to Discourage Self-Medication

Pharmacists and medicine retailers have also been instructed not to encourage or facilitate self-medication involving prescription-only NSAIDs and antibiotics.

Most NSAIDs fall under prescription requirements, while many antibiotics are subject to stricter controls under India’s drug regulations.

Medicines covered by these rules should be sold according to their applicable prescription requirements.

Hospitals Asked to Strengthen Monitoring

Hospitals and other healthcare institutions have been advised to strengthen systems for the rational prescribing and monitoring of painkillers and antibiotics.

Healthcare facilities are expected to encourage appropriate use, monitor adverse effects and ensure medicines are being prescribed according to clinical requirements.

Improper Antibiotic Use Raises Resistance Concerns

Unnecessary or incorrect antibiotic consumption also contributes to antimicrobial resistance, a growing global health challenge.

Resistance develops when bacteria evolve in ways that reduce the effectiveness of medicines used to treat infections.

This can make previously manageable infections more difficult to treat and increase the need for stronger or more expensive medicines.

Chronic Kidney Disease Remains Major Health Concern

Kidney disease has emerged as an important public-health concern in India.

Damage to the kidneys may develop gradually and can go unnoticed during its earlier stages, making prevention and responsible medicine use particularly important.

Long-term misuse of certain medications can add to kidney-related risks, especially among people who already have underlying health problems.

Patients Advised Not to Stop Prescribed Medicines on Their Own

The warning does not mean patients should stop medically prescribed painkillers or antibiotics without consulting their healthcare provider.

Instead, the emphasis is on avoiding self-medication, excessive doses and prolonged use without professional supervision.

Patients taking prescribed medicines should follow the dose and duration recommended by their doctor and seek medical advice if they experience unusual symptoms or side effects.

Awareness Drive to Promote Safer Medicine Use

Drug-control authorities have also been asked to increase awareness among healthcare professionals, pharmacists, retailers and the general public.

The broader objective is to promote responsible medicine use and reduce avoidable kidney complications associated with inappropriate consumption of painkillers and antibiotics.

The advisory was formally dated September 21, 2026, and has received renewed attention on September 28 amid fresh reporting on painkiller misuse and kidney risks.

Source – Central Drugs Standard Control Organisation / Times of India / Economic Times CDSCO

Supreme News Network

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